Naima Jabeen BDS
Sarah Ghafoor BDS, PhD
Chronic periodontitis is a slow progressing disease of oral tissue that causes inflammation and bleeding of gingiva. If it is untreated, it leads to periodontal pockets, loosening of teeth and ultimate tooth loss. Saliva is a hypertonic fluid present in the oral cavity that is now used as a diagnostic tool. Saliva contains water, organic and inorganic molecules that can act as biomarkers for systemic and oral diseases. Presence of these biomarkers in saliva can help in the early detection of chronic periodontitis disease for therapeutic purpose. This review summarizes the salivary biomarkers that can help in early detection and diagnosis of chronic periodontitis disease.
KEY WORDS: Chronic periodontitis, salivary biomarkers, systemic diseases, oral diseases.
HOW TO CITE: Jabeen N, Ghafoor S. Salivary biomarkers of chronic periodontitis. J Pak Dent Assoc 2019;28(4):197-200.
Received: 21 November 2018, Accepted: 08 August 2019