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Polymorphous Adenocarcinoma (PAC) - JPDA

Polymorphous Adenocarcinoma (PAC)

Humayun Kaleem Siddiqui1                         BDS, FCPS

Ausaf Ahmed Khan2                                                   MBBS, FCPS

Sharjeel Bashir3                                              BDS

Syed Muratza Raza Kazmi4                           BDS, FCPS

ABSTRACT: Polymorphous adenocarcinoma (PAC) is almost entirely related to minor salivary glands. It is mostly found in the palatal region but on rare it was also observed in other intraoral areas. In recent studies it is observe that there is a potential for histological transformation of the lesion from low to high grade malignancy.

CASE REPORT: A 52 year old male reported to Memon Medical Institute Hospital dental OPD with growth on hard plate for 6 months and mobility of teeth. The lesion was painless with no signs of ocular involvement. Lesion was extending from premaxillary region covering whole of the hard palate to soft palate and beyond. CT scan showed heterogenous enhancing mass with calcifications probably arising from alveolar process of left upper jaw causing complete destruction of left alveolar processes with maxillary bone and hard palate. A plan for total maxillectomy was discussed with the patient and the defect to be filled with a hollow acrylic obturator. On 2 year follow-up, the patient was doning well with no signs of recurrence.

KEY WORDS:  Adenocarcinoma, Palate, Salivary glands, Tumour.

HOW TO CITE: Siddiqui HK, Khan AA, Bashir S, Kazmi SMR. Polymorphous adenocarcinoma (PAC). J Pak Dent Assoc 2018;27(3):152-56.

DOI: https://doi.org/10.25301/JPDA.273.152

Received: 05 October 2017, Accepted: 15 February 2018