Identification of Orthodontic Extraction Predictors in End-On Class II Malocclusion


 Batool Ali                                     BDS, FCPS     

 Waqar Jeelani                              BDS, FCPS

 Attiya Shaikh                               BDS, M.Orth, FCPS

 Tabassum Ahsan Quadeer        BDS, FCPS    

 Javeria Ali Khan                         BDS, FCPS

OBJECTIVE: This study was designed to determine the different treatment predictors which help in the extraction and non-extraction decision of an end-on Class II malocclusion case.
METHODOLOGY: The pretreatment records of 240 adult subjects aged 15-40 years with bilateral end-on Class II molar relationship were retrospectively selected and categorized under extraction (120) and non-extraction (120) treatment categories. The extraction cases were planned for different combinations of premolar extractions. The independent variables i.e., the cephalometric and orthodontic cast measurements were obtained from the recruited sample. Binary logistic regression analysis was applied using SPSS software.
RESULTS: Increased upper and lower incisor inclinations (p < 0.001) and procumbent upper lip (p = 0.004) was statistically significant in the extraction group. According to the regression model, the odds of extraction treatment were 1.12 times greater than non-extraction treatment for every one degree increase in upper and lower incisor inclinations, respectively. The chances of extraction treatment were 1.6 times higher than non-extraction treatment for every 1 mm increase in the distance of upper lip to S-plane.
CONCLUSIONS: The upper and lower incisors inclinations and upper lip position are the critical factors affecting the extraction decision in adult patients with end-on Class II molar relationships. Overjet, dental crowding and the vertical growth pattern were found to be clinically insignificant in opting for an extraction treatment plan for such cases.
KEYWORDS:Treatment, Angle Class II, tooth extraction, non-extraction
HOW TO CITE: Ali B, Jeelani W, Shaikh A, Quadeer TA, Khan JA. Identification of orthodontic extraction predictors in endon class II malocclusion. J Pak Dent Assoc 2021;30(3):178-182 .
Received: 13 March 2021, Accepted: 21 June 2021

Class II malocclusion can be treated via different therapeutic approaches depending on the severity of malocclusion and growth status of an individual. Patients presenting in the prepubertal or pubertal growth period are routinely treated with dento-facial orthopedics to correct the skeletal deformity.1,2 Adult patients with no growth potential require comprehensive treatment planning to decide between orthodontic camouflage and surgical treatment. Non extraction decision with molar distalization, extraction patterns including four premolars, one from each quadrant, or in special scenarios, asymmetric extraction or molar extractions are carried out to achieve acceptable dento-facial esthetics with stable occlusion.
The orthodontic diagnosis and treatment planning involves the process of identifying the correct etiology and
designing an individualized treatment plan. The decision to extract or not extract is greatly influenced by parameters
like incisor proclination, lip incompetency, procumbent or recumbent lip profile, level of crowding in one or both
arches, midline discrepancy, molar relationship and the complexity of the malocclusion.5-8 Although the above mentioned factors play an essential role in planning process,yet, a comprehensive plan must be generated for every
individual without limiting it to the obvious quantitative variables.
The rationale behind conducting this study was that class II correction protocols till date remain a controversial
issue and orthodontists agree that stability of a class II corrected case is as important as the facial harmony and
esthetic balance. Hence, the variables that could help in planning a case with the best possible patient-oriented approach that not only improvises the orofacial esthetics but also gives long term stability to a class II malocclusion
needs yet to be identified. According to a pertinent literature survey, none of the studies have yet uncovered the variables which account for favoring an extraction approach over a non-extraction approach and vice versa in end on Class II cases that could accelerate the decision making process and establish evidence based predictors for planning such cases. Due to the absence of a proper guideline or potent evidence, the treatment planning process generally
is more dependent on a subjective approach via clinician’s personal experiences, treatment philosophy and mode of
Therefore, the objective of this study was designed to review the pretreatment records of patients with end-on
Class II malocclusion and compare the initial morphologic characteristics of patients diagnosed and planned by two
expert clinicians in order to determine the different treatment predictors which can help a clinician in the extraction and non-extraction decision of an end-on Class II malocclusion case.

       Records of 1500 orthodontic patients were screened from the orthodontic clinics of a total of 400 pre-treatment
records having Class II malocclusion with a half unit molar relationship was sorted. A molar relationship was considered end-on if the mesio-buccal cusp tip of maxillary first molar in occlusion was > 3 mm and < 4 mm mesial to the buccal groove of lower first molar.1 An ethical exemption was taken from the institutional review board before data collection (4078-Sur-ERC-17). The sample size was calculated as 120 records in each group using Open Epi software using the mean values of Li:NB distance from a study conducted by Bishara et al13 with a value of 0.6 ± 1.8 mm for the extraction group and 1.2 ± 1.5 mm for the non-extraction group at a CI of 95% and keeping the power of study as 80%. The orthodontic records were carefully selected using simple random sampling method. Orthodontic record of each patient was critically evaluated on a routine basis by a team of orthodontists to formulate the most efficient treatment plan for that particular individual. The extraction cases selected for the study were those planned
by expert clinicians for different combinations of premolar extractions. The non-extraction cases planned to be treated by molar distalization were selected for the study.
The following criteria was established for the orthodontic records to be included in the current study. Good quality complete dental records with healthy dentition having bilateral end-on Class II molar relations. Subjects
with any history of trauma, syndromes or craniofacial anomalies, and those undergone previous orthodontic treatment were excluded from the study. The lateral cephalograms carried out for orthodontic analysis were recorded in natural head position by the same machine for each individual. The head was positioned parallel to the
Frankfurt horizontal plane with teeth positioned in centric occlusion. These radiographs were standardized with rigid head fixation, 152-cm
source to the mid-sagittal plane distance and 15 cm film to the mid-sagittal plane distance using Orthoralix® 9200
(Gendex-KaVo, Milan, Italy).14
The mill metric measurements (overbite, overjet, dental midlines, maxillary and mandibular space analysis) on
dental casts were carried out using a digital vernier caliper (0-150mm ME00183, Dentaurum, Pforzheim, Germany)
with accuracy of 0.02 mm and reliability of 0.01 mm as per manufacturer’s specification. The measurement done
on orthodontic casts included: overjet, overbite, upper and lower dental midlines and maxillary (Mx-TSALD) and
mandibular tooth size arch length discrepancy (Md-TSALD). Lateral cephalograms were traced, landmarks were identifiedand planes were constructed according to the standard definitions given in orthodontic books and literature. Cephalometric measurements derived from the landmarks and planes included: SNA, SNB, ANB, Wits appraisal, Nasion perpendicular to point A, Nasion perpendicular to Pogonion SN-Go.Gn, FHMP, lower anterior facial height (LAFH), UI-SN, IMPA, nasolabial angle, and relationship of upper and lower lips to E and S planes.
Repeated measurements of 25 randomly selected dental casts and cephalometric radiographs were made 2 months
after the initial assessment and ICC was used to evaluate the reliability of repeated measurements. The ICC showed
a value of 0.80 for the variables assessed.

      The statistical analysis was undertaken using the SPSS software for Windows (version 22 .0; SPSS, Chicago, Ill).
Means and SD’s were calculated for the independent variables. Binary logistic regression was applied to evaluate the effect of independent variables on the treatment outcome. The binary logistic regression technique is most often used to model the relationship between a binary outcome variable and a set of covariates. The binary outcome variables was the treatment decision, whereas, the measurements attained from cephalometric analysis and orthodontic casts were categorized as independent variables. Multicollinearity of the independent variables was also assessed. A value of greater than 0.83 was considered as highly significantly correlated, hence, only one of the variable was used for the final logistic model.

      The descriptive statistics are summarized in Table 1. The ANB angle, Nasion perpendicular to Pogonion, the
vertical facial pattern, the upper and lower incisor

inclinations, overjet, Md-TSALD and the relation of both the lips to E-plane and S-plane, respectively, were
significantly different between both the non-extraction and extraction groups in the univariate model generated after
the initial regression analysis as shown in Table 2. Table 3 shows the final multivariable model. According to the statistical results, one skeletal, one soft tissue and three

Dental variables showed a significant difference between the treatment groups. In an end-on class II malocclusion,
the odds of extraction treatment were 1.12 times that of non-extraction treatment for every one degree upsurge in upper and lower incisor inclinations, respectively. Similarly, chances of extraction treatment were 1.6 times higher than non-extraction treatment for every 1 mm increase in the distance of upper lip to S-plane. The regression model states that a Class II malocclusion with half-unit molar relationship having increased upper and lower incisor inclinations and procumbent upper lip has a greater chance of being efficiently treated by extraction mechanics.
Class II malocclusion is one of the most prevailing malocclusions in our society.15,16 The orthodontists are interested in gaining knowledge about selective parameters that could help in efficient and accurate treatment planning. Taking into consideration the soft tissue, dental cast and cephalometric values, an objective and quantifiable treatment plan could be generated for a specific individual. A full unit Class II molar relationship is usually treated with extraction, myo-functional therapy or, if the skeletal malocclusion warrants, orthognathic surgery. However, in suitable cases full unit Class II molar relationship can be corrected by non-extraction treatment strategies like molar distalization or bite jumper appliances, but these techniques are not routinely implemented .1
On the other hand, end-on or half unit Class II molar relationship is frequently treated by both extraction and non-extraction strategies and it is not uncommon among clinicians to have variable opinion on extraction decision in such cases.
According to the statistical results of this study, the upper and lower incisor proclination and a procumbent upper lip favors an extraction decision. An odds ratio of greater than 1 in the study results is suggestive of extraction plan. An end-on class II malocclusion presents with either a normal or prognathic maxilla or a deficient mandible. In some
scenarios the maxillary incisors are proclined creating increased upper lip prominence with acuteness of nasolabial
angle.1 Instead, in mandibular deficient cases natural compensations are present in the form of proclined lower
incisors.1 Hence treatment planning of a Class II division 1 case essentially require a four unit extraction to correct the facial esthetics, lip prominence and improve stability of occlusion with moving the incisors within the normal range. Few studies have focused on the factors that help towards the decision making process of a Class II malocclusion. The results of Paquette and co authors17 also indicate that convex facial profiles and proclined upper and lower incisors are major contributors towards an extraction decision. Similarly Bishara and associates13 stated that lip prominence, crowded arches and a Class II molar relationship is suggestive of an extraction decision. On the contrary, Guo et al18 reported that the most important factors guiding towards an extraction decision in Class II cases are increased overjet, vertical growth pattern and crowded arches. Likewise, according to Shearn and Woods19, incisor overjet is one of the major factor influencing the extraction decision. Analogous to the results of our study, Ali et al20, and Konstantonis and co-workers21 reported that incisor proclination, lip prominence and crowded arches are also one of the deciding factors in treatment of a Class I malocclusion.
The results of the current study based on end-on Class II molar relationship is dissimilar to the results of previous
studies in a few aspects.17-20 Firstly, the overjet was not found to play a significant role in the extraction decision of end-on Class II molar relationship patients. Secondly, crowding which has been shown to play a key role in Class I and full unit Class II malocclusion cases, was found to play no significant role in extraction decision in cases with end-on Class II molar relationship. These results suggest that less severe Class II malocclusion, with increased overjet or mild to moderate crowding or both could be efficiently managed with a non-extraction therapeutic approach. In such cases, the clinicians could use different non-extraction modalities for correcting the crowding and molar relationship.
It is worth mentioning that the clinicians experience, biomechanical strategies and esthetic sense also has an
impact on the treatment planning process, hence, the variation in results are found among different studies as these
subjective variables are difficult to quantify.

     The study, although, included a fairly large sample but the sample was collected from a single tertiary care center
undermining the generalizability of the results. Besides, the norms of diagnostic parameters and morphological characteristics have certain ethnic variations which could affect the treatment decision. The authors recommend recruiting the sample from multiple institutes to give more predictable and generalizable results in future studies.

      The current study concludes that upper and lower incisors inclinations and upper lip position are the
critical factors affecting the extraction decision in adult patients with end-on Class II molar relationships. Overjet,
dental crowding and the vertical growth pattern formerly reported to be other key factors in extraction decision of
orthodontic patients were found to play no significant role in extraction decisionof patients with end-on Class II molar relationship.

None to declare



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