Assessment of Alkaline Phosphatase in Crevicular Fluid of Adolescent Undergoing Rapid Maxillary Expansion


Ahmad Shamim Qureshi     BDS, MDS
Asmi Shaheen                      BDS, FCPS
Hafiza Asma Javed              BDS, MDS
Samina Qadir                       BDS, MDS
Shabbir Hussain                  BDS, MDS.
Nauman Sadiq                      BDS, MDS


OBJECTIVE: The objectives of this study were to observe the changes in enzyme behavior during Orthodontic tooth movement and Rapid Maxillary expansion to predict the exact timing for Commencement of treatment in young children. 
METHODOLOGY: We selected fifteen patients having age between 9-15 years. Periodontal protocols (Samples from buccal and palatal side) were observed and sample collection before initiation of treatment, during and after activation was done from patients requiring RME. The GCF and ALP activity was checked at the experimental location.
RESULTS: The initial enzyme activity in GCF and ALP was calculated between the buccal and Control sites during maxillary expansion. It was observed that during activation of the appliance and then after 3 months of retention period a significantly elevated enzyme levels were still noted at the experimental sites.
CONCLUSION: An Increase in osteoblastic activity during adolescence period can predict commencement of early or delayed intervention for most favorable treatment results.
HOW TO CITE: Qureshi AS, Shaheen A, Javed HA, Qadir S, Hussain S, Sadiq N. Assessment of alkaline phosphatase in crevicular fluid of adolescent undergoing rapid maxillary expansion. J Pak Dent Assoc 2022;31(4):161-164.
Received: 28 February 2022, Accepted: 16 November 202

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